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慢性非肉芽肿性会厌炎:一种罕见且难治的疾病。

Chronic non-granulomatous supraglottitis: a rare and difficult disease.

作者信息

Ledgerwood L G, Belafsky P C

机构信息

Center for Voice and Swallowing, University of California, Sacramento, CA 95817, USA.

出版信息

J Laryngol Otol. 2012 Aug;126(8):854-7. doi: 10.1017/S0022215112000977. Epub 2012 May 29.

DOI:10.1017/S0022215112000977
PMID:22642797
Abstract

OBJECTIVES

To examine chronic non-granulomatous supraglottitis, a rare disorder of uncertain aetiology with few reported cases in the literature.

CASE REPORTS

We describe two cases of chronic non-granulomatous supraglottitis that led to persistent respiratory compromise. Patients underwent extensive investigation that failed to reveal a definitive diagnosis.

CONCLUSION

In patients suffering from chronic inflammation of the supraglottic larynx without evidence of infection, neoplasm or granulomatous disease, many disorders must be ruled out in order to diagnose chronic non-granulomatous supraglottitis, which is a diagnosis of exclusion. We review the literature on this rare entity, discuss current management strategies, and suggest an algorithm for diagnostic investigation.

摘要

目的

研究慢性非肉芽肿性会厌炎,这是一种病因不明的罕见疾病,文献报道的病例较少。

病例报告

我们描述了两例导致持续性呼吸功能不全的慢性非肉芽肿性会厌炎病例。患者接受了广泛检查,但未能明确诊断。

结论

对于患有会厌慢性炎症但无感染、肿瘤或肉芽肿性疾病证据的患者,为诊断慢性非肉芽肿性会厌炎(一种排除性诊断),必须排除许多疾病。我们回顾了关于这一罕见疾病的文献,讨论了当前的管理策略,并提出了诊断性检查的流程。

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引用本文的文献

1
Chronic non-granulomatous supraglottitis of a male adolescent and its successful management with azathioprine.一名男性青少年的慢性非肉芽肿性会厌上炎及其用硫唑嘌呤的成功治疗
BMJ Case Rep. 2019 Apr 3;12(4):e227458. doi: 10.1136/bcr-2018-227458.