Department of Pediatric Radiology, Hospital Universitario Vall d'Hebron - AMI, Ps. Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Pediatr Radiol. 2012 Aug;42(8):916-22. doi: 10.1007/s00247-012-2362-x. Epub 2012 May 29.
Fetuses with severe congenital diaphragmatic hernia (CDH) and pulmonary hypoplasia may benefit from fetal endoluminal tracheal occlusion (FETO). Enlargement of the main bronchi and trachea appears to be a common complication of FETO.
To retrospectively evaluate the trachea and main bronchi of infants who underwent FETO for CDH and compare diameters with age-matched references.
Postnatal and follow-up chest radiographs were performed in seven children with unilateral CDH treated by FETO. Additional CT was performed in six of these (one neonate died before CT could be performed). Images were acquired from 3 days to 23 months of age. For each child, radiographs and CT images with optimal visualisation of the airways were selected for retrospective analysis. Tracheal and bronchial morphology was assessed by two experienced paediatric radiologists, and the diameters of these structures measured and compared with age-matched references.
Mean diameters of the trachea and main bronchi were above the age-matched normal range in all patients, regardless of the side of the hernia or the degree of lung hypoplasia.
Enlargement of the trachea and main bronchi appears following FETO and persists at least to the age of 5 years.
患有严重先天性膈疝（CDH）和肺发育不良的胎儿可能受益于胎儿腔内气管阻塞（FETO）。FETO 似乎是主要支气管和气管扩大的常见并发症。
回顾性评估接受 FETO 治疗的 CDH 婴儿的气管和主支气管，并与年龄匹配的参考值进行比较。
对 7 例接受 FETO 治疗的单侧 CDH 婴儿进行了产后和随访胸部 X 线检查。其中 6 例进一步进行了 CT（1 例新生儿在进行 CT 检查前死亡）。在 3 天至 23 个月的年龄范围内采集了图像。对于每个孩子，选择最佳显示气道的 X 线片和 CT 图像进行回顾性分析。两名有经验的儿科放射科医生评估了气管和支气管的形态，并测量了这些结构的直径，并与年龄匹配的参考值进行了比较。
所有患者的气管和主支气管直径均高于年龄匹配的正常范围，无论疝的部位或肺发育不良的程度如何。
FETO 后气管和主支气管增大，并至少持续到 5 岁。
