Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
Arch Pathol Lab Med. 2012 Jun;136(6):668-78. doi: 10.5858/arpa.2011-0274-SO.
Pathologists have long served as custodians of human biospecimens collected for diagnostic purposes. Rapid advancements in diagnostic technologies require that pathologists change their practices to optimize patient care. The proper handling of biospecimens creates opportunities for pathologists to improve their diagnoses while assessing prognosis and treatment. In addition, the growing need for high-quality biorepositories represents an opportunity for community pathologists to strengthen their role within the health care team, ensuring that clinical care is not compromised while facilitating research. This article provides a resource to community pathologists learning how to create high-quality biorepositories and participating in emerging opportunities in the biorepository field. While a variety of topics are covered to provide breadth of information, the intent is to facilitate a level of understanding that permits community pathologists to make more informed choices in identifying how best their skills and practice may be augmented to address developments in this field.
病理学家长期以来一直负责保管为诊断目的而收集的人体生物标本。诊断技术的快速发展要求病理学家改变实践方法,以优化患者护理。正确处理生物标本为病理学家提供了机会,可以改善诊断,同时评估预后和治疗。此外,高质量生物库的需求不断增长,为社区病理学家在医疗保健团队中加强角色提供了机会,确保在促进研究的同时不会影响临床护理。本文为学习如何创建高质量生物库并参与生物库领域新兴机会的社区病理学家提供了资源。虽然涵盖了各种主题以提供广泛的信息,但目的是促进一定程度的理解,使社区病理学家能够更明智地选择如何最好地增强他们的技能和实践,以应对该领域的发展。