Poulain D
Service de Parasitologie-Mycologie, Faculté de Médecine, Lille.
Ann Parasitol Hum Comp. 1990;65 Suppl 1:125-30. doi: 10.1051/parasite/1990651125.
Candida albicans is a versatile organism living as a commensal of the gastro-intestinal tract and having the ability to invade host tissues and to initiate serious diseases under the appropriate environmental conditions. The molecular basis for adherence, invasion, interactions with specific and non-specific immune factors have been studied in parallel to structural characteristics of the yeast. The main parasitologic features are closely linked to phenotypic variations. In this respect, mannoproteins are strongly involved in the cell wall variations. The study of the oligomannosidic repertoire represents one of the essential steps for the understanding of host-parasite relationships.
白色念珠菌是一种多面性的生物体，作为胃肠道的共生菌存在，并能够在适当的环境条件下侵入宿主组织并引发严重疾病。人们在研究酵母结构特征的同时，也对其黏附、侵袭以及与特异性和非特异性免疫因子相互作用的分子基础进行了研究。其主要寄生虫学特征与表型变异密切相关。在这方面，甘露糖蛋白在细胞壁变异中起着重要作用。对寡甘露糖库的研究是理解宿主 - 寄生虫关系的关键步骤之一。
