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[二氧化嘧啶对金黄色葡萄球菌细胞外蛋白质和酶的影响]

[Effect of dioxidine on extracellular proteins and enzymes in Staphylococcus aureus].

作者信息

Fadeeva N I, Degtiareva I N, Fominova A N, Degteva G K

出版信息

Antibiot Khimioter. 1990 Aug;35(8):17-20.

PMID:2264746
Abstract

Dioxidine++-induced changes were shown to occur in the protein composition of the cells of Staphylococcus aureus. The most significant damages were observed in the composition of exoproteins. Dioxidine++ had a specific inhibitory effect on intracellular nuclease, which was accompanied by a decrease in virulence and disorders in the toxin formation.

摘要

二氧二菌素++诱导的变化显示发生在金黄色葡萄球菌细胞的蛋白质组成中。在外毒素蛋白组成中观察到最显著的损伤。二氧二菌素++对细胞内核糖核酸酶有特异性抑制作用,这伴随着毒力降低和毒素形成紊乱。

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