Wilkening Greta N, Madden Jennifer R
University of Colorado, Aurora, CO, USA.
J Pediatr Oncol Nurs. 2012 May-Jun;29(3):161-70. doi: 10.1177/1043454212439938.
Memory disorders in children and adolescents with brain tumors are rare, but devastating to social, academic, and vocational development. Many pediatric patients with intracranial germ cell tumors (GCTs) complain of memory difficulties. This study investigated memory across a series of GCT patients. A total of 33 GCT patients were retrospectively examined for diagnosis, imaging results, intelligence quotient, treatment variables, evidence of increased intracranial pressure at diagnosis, and memory. The incidence of amnesia in GCT patients was 55%. Memory disturbance could not be predicted by intelligence quotient, treatment, location of lesion, or hydrocephalus at diagnosis. The high incidence of memory deficits in GCT patients suggests a risk to memory in patients with GCT. Formal memory assessment should be considered in all patients with central nervous system GCTs. Specific counseling and planning to assist in adjustment and to ensure safety should be considered standard care for those with memory deficits. The nurse should be instrumental in facilitating understanding of this specific injury in the brain tumor population.
脑肿瘤患儿和青少年的记忆障碍较为罕见，但对其社交、学业和职业发展具有毁灭性影响。许多患有颅内生殖细胞肿瘤（GCT）的儿科患者都抱怨存在记忆困难。本研究调查了一系列GCT患者的记忆情况。总共对33例GCT患者进行了回顾性检查，内容包括诊断、影像学结果、智商、治疗变量、诊断时颅内压升高的证据以及记忆情况。GCT患者中失忆症的发生率为55%。记忆障碍无法通过智商、治疗、病变位置或诊断时的脑积水情况来预测。GCT患者中记忆缺陷的高发生率表明GCT患者存在记忆风险。所有中枢神经系统GCT患者都应考虑进行正式的记忆评估。对于有记忆缺陷的患者，应考虑提供特定的咨询和规划，以协助其调整并确保安全，这应被视为标准护理。护士应在促进对脑肿瘤患者这一特定脑部损伤的理解方面发挥作用。
