Stanford Health Policy, Department of Medicine, Stanford University, Stanford, California (JGF, RR, JB)
Department of Pediatrics, Stanford University, Stanford Prevention Research Center, Department of Medicine, Stanford University, and Center for Policy, Outcomes and Prevention, Lucile Packard Children’s Hospital, Stanford, California (TR)
Med Decis Making. 2013 Feb;33(2):163-75. doi: 10.1177/0272989X12447240. Epub 2012 May 29.
High childhood obesity prevalence has raised concerns about future adult health, generating calls for obesity screening of young children.
To estimate how well childhood obesity predicts adult obesity and to forecast obesity-related health of future US adults.
Longitudinal statistical analyses; microsimulations combining multiple data sets.
National Longitudinal Survey of Youth, Population Study of Income Dynamics, and National Health and Nutrition Evaluation Surveys.
The authors estimated test characteristics and predictive values of childhood body mass index to identify 2-, 5-, 10-, and 15 year-olds who will become obese adults. The authors constructed models relating childhood body mass index to obesity-related diseases through middle age stratified by sex and race.
Twelve percent of 18-year-olds were obese. While screening at age 5 would miss 50% of those who become obese adults, screening at age 15 would miss 9%. The predictive value of obesity screening below age 10 was low even when maternal obesity was included as a predictor. Obesity at age 5 was a substantially worse predictor of health in middle age than was obesity at age 15. For example, the relative risk of developing diabetes as adults for obese white male 15-year-olds was 4.5 versus otherwise similar nonobese 15-year-olds. For obese 5-year-olds, the relative risk was 1.6.
Main results do not include Hispanics due to sample size. Past relationships between childhood and adult obesity and health may change in the future.
Early childhood obesity assessment adds limited information to later childhood assessment. Targeted later childhood approaches or universal strategies to prevent unhealthy weight gain should be considered.
儿童肥胖率高,引发了对未来成人健康的担忧,呼吁对幼儿进行肥胖筛查。
评估儿童肥胖对成人肥胖的预测能力,并预测未来美国成年人肥胖相关的健康状况。
纵向统计分析;结合多个数据集的微观模拟。
全国青少年纵向调查、收入动态人口研究和国家健康与营养调查。
作者估计了儿童体重指数的检测特征和预测值,以识别出将成为肥胖成年人的 2 岁、5 岁、10 岁和 15 岁儿童。作者通过性别和种族分层,构建了将儿童体重指数与中年肥胖相关疾病相关联的模型。
18 岁时,有 12%的人肥胖。虽然在 5 岁时进行筛查会错过 50%的肥胖成年人,但在 15 岁时进行筛查会错过 9%。即使将母亲肥胖作为预测因素纳入,10 岁以下儿童肥胖筛查的预测价值也很低。与 15 岁时肥胖相比,5 岁时肥胖是中年健康状况的一个更糟糕的预测因素。例如,肥胖白人男性 15 岁的成年人患糖尿病的相对风险为 4.5,而其他相似的非肥胖 15 岁的成年人相对风险为 4.5。对于肥胖的 5 岁儿童,相对风险为 1.6。
由于样本量的原因,主要结果不包括西班牙裔。儿童期和成年期肥胖与健康之间的过去关系可能会在未来发生变化。
早期儿童肥胖评估对后期儿童评估增加的信息量有限。应考虑针对后期儿童的特定方法或预防体重不健康增加的普遍策略。