Center for Health Research, Geisinger Clinic, 100 North Academy Avenue, Danville, PA 17822-4400, USA.
Psychiatry Res. 2012 Dec 30;200(2-3):827-34. doi: 10.1016/j.psychres.2012.04.022. Epub 2012 May 29.
We previously developed a new posttraumatic stress disorder (PTSD) screening instrument-the New York PTSD Risk Score (NYPRS). Since research suggests different PTSD risk factors and outcomes for men and women, in the current study we assessed the suitability of male and female versions of this screening instrument among 3298 adults exposed to traumatic events. Using diagnostic test methods, including receiver operating characteristic (ROC) curve and bootstrap techniques, we examined different prediction domains, including core PTSD symptoms, trauma exposures, sleep disturbances, depression symptoms, and other measures to assess PTSD prediction models for men and women. While the original NYPRS worked well in predicting PTSD, significant interaction was detected by gender, suggesting that separate models are warranted for men and women. Model comparisons suggested that while the overall results appeared robust, prediction results differed by gender. For example, for women, core PTSD symptoms contributed more to the prediction score than for men. For men, depression symptoms, sleep disturbance, and trauma exposure contributed more to the prediction score. Men also had higher cut-off scores for PTSD compared to women. There were other gender-specific differences as well. The NYPRS is a screener that appears to be effective in predicting PTSD status among at-risk populations. However, consistent with other medical research, this instrument appears to require male and female versions to be the most effective.
我们之前开发了一种新的创伤后应激障碍(PTSD)筛查工具——纽约 PTSD 风险评分(NYPRS)。由于研究表明男性和女性 PTSD 的风险因素和结果不同,因此在当前研究中,我们评估了该筛查工具的男性和女性版本在 3298 名暴露于创伤性事件的成年人中的适用性。我们使用诊断测试方法,包括接收者操作特征(ROC)曲线和自举技术,研究了不同的预测领域,包括核心 PTSD 症状、创伤暴露、睡眠障碍、抑郁症状和其他评估 PTSD 预测模型的指标,以评估男性和女性的 PTSD 预测模型。虽然原始的 NYPRS 在预测 PTSD 方面表现良好,但性别存在显著交互作用,表明需要为男性和女性分别建立模型。模型比较表明,尽管整体结果似乎稳健,但预测结果因性别而异。例如,对于女性,核心 PTSD 症状对预测分数的贡献大于男性。对于男性,抑郁症状、睡眠障碍和创伤暴露对预测分数的贡献更大。男性的 PTSD 截断分数也高于女性。也存在其他性别特异性差异。NYPRS 是一种筛查工具,似乎可以有效地预测高危人群的 PTSD 状况。然而,与其他医学研究一致,该工具似乎需要男性和女性版本才能达到最佳效果。