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Vector systems for prenatal gene therapy: choosing vectors for different applications.

作者信息

Coutelle Charles, Waddington Simon N

机构信息

National Heart and Lung Institute, Molecular and Cellular Medicine Section, Imperial College London, London, UK.

出版信息

Methods Mol Biol. 2012;891:41-53. doi: 10.1007/978-1-61779-873-3_3.

Abstract

This chapter gives a comparative review of the different vector systems applied to date in prenatal gene therapy experiments highlighting the need for versatility and choice for application in accordance with the actual aim of the study. It reviews the key characteristics of the four main gene therapy vector systems and gives examples for their successful application in prenatal gene therapy experiments.

摘要

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