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早产儿视网膜病变:我们是否漏诊了任何早产儿视网膜病变患儿?

Retinopathy of prematurity: are we missing any infant with retinopathy of prematurity?

机构信息

Department of Ophthalmology, King Fahad Military Hospital, Armed Forces Hospitals, Khamis Mushait, Saudi Arabia.

出版信息

Br J Ophthalmol. 2012 Aug;96(8):1052-5. doi: 10.1136/bjophthalmol-2012-301570. Epub 2012 May 30.

DOI:10.1136/bjophthalmol-2012-301570
PMID:22649086
Abstract

AIMS

To evaluate incidence of retinopathy of prematurity (ROP) and validity of current ROP screening criteria adopted in the Armed Forces Hospitals.

METHODS

A retrospective study of ROP indices was carried out in infants admitted to the neonatal intensive care unit in Khamis Mushait, Saudi Arabia, from January 2009 to December 2011. All infants who had birth weight (BW) of 1500 g or less and/or gestational age (GA) of 32 weeks or less had their data reviewed for ROP diagnosis and related indices. Some heavier or older infants were also included in the study.

RESULTS

386 infants were screened and ROP was diagnosed in 90 infants (23.31%). 25 infants (6.47%) had type 1 or worse ROP and were treated with cryopexy or laser. For patients having ROP, the mean GA was 27.8 ± 2 weeks and mean BW was 961.8 ± 237.4 g. Infants who needed treatment for ROP had a mean BW of 828.8 ± 192.8 g and mean GA of 27 ± 1.8 weeks. All infants who developed ROP fulfilled both or one criterion of ROP screening. No infant greater than 1350 g BW or more than 31 weeks GA was treated for ROP.

CONCLUSIONS

Current ROP screening criteria of BW of 1500 g or less and/or GA of 32 weeks or less seems reasonable in our set up as no infant having ROP was missed by using these criteria. We do not recommend lowering or using only one index for ROP screening.

摘要

目的

评估早产儿视网膜病变(ROP)的发生率和沙特阿拉伯哈米斯穆沙伊特武装部队医院采用的现行ROP 筛查标准的有效性。

方法

对 2009 年 1 月至 2011 年 12 月期间在新生儿重症监护病房住院的婴儿进行 ROP 指数的回顾性研究。所有出生体重(BW)为 1500g 或以下和/或胎龄(GA)为 32 周或以下的婴儿均对 ROP 诊断和相关指数进行了数据复查。一些较重或较大的婴儿也被纳入了研究。

结果

共筛查了 386 名婴儿,90 名婴儿(23.31%)被诊断为 ROP。25 名婴儿(6.47%)患有 1 型或更严重的 ROP,并接受冷冻或激光治疗。对于患有 ROP 的患者,平均 GA 为 27.8 ± 2 周,平均 BW 为 961.8 ± 237.4g。需要治疗 ROP 的婴儿的平均 BW 为 828.8 ± 192.8g,GA 为 27 ± 1.8 周。所有发展为 ROP 的婴儿均符合 ROP 筛查的两项或一项标准。没有体重超过 1350g 或胎龄超过 31 周的婴儿因 ROP 而接受治疗。

结论

在我们的研究中,目前以 BW 小于 1500g 和/或 GA 小于 32 周作为 ROP 筛查标准似乎是合理的,因为没有一个患有 ROP 的婴儿被遗漏。我们不建议降低或仅使用一个 ROP 筛查指标。

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