Beden Umit, Demir Selim, Aygün Canan, Küçüködük Sükrü, Erkan Dilek
Department of Ophthalmology, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey.
Turk J Pediatr. 2012 May-Jun;54(3):223-9.
This study was designed to determine the frequency of retinopathy of prematurity (ROP) and the effectiveness of the screening protocol in preterm infants for our country. With these objectives, the charts of 1000 preterm infants were reviewed in Ondokuz Mayis University, Department of Ophthalmology. ROP frequency, the effect of gestational age (GA) and birth weight (BW) and the effectiveness of the screening protocol were evaluated. In this study, ROP was observed in 30.8% of infants and not observed in 69.2% of infants. Threshold ROP was detected in 7.0%. The frequency of threshold ROP was 43.5%, 20.0%, 12.6%, and 8.8% in the infants with GA of < or = 26, 26-28, 29-30, and 31-32 weeks, respectively. Threshold ROP was not observed in babies born after 34 weeks. Treatment was required for 11% of the infants. ROP treatment requirement (11%) was limited to babies with GA of < 34 weeks of gestation. Incidence of ROP was inversely proportional with GA and BW. Treatment was not required when GA was > 34 weeks. A new ROP screening protocol is proposed for Turkey, which is: screening of preterm babies with GA of < 34 weeks and BW of < 1800 g.
本研究旨在确定我国早产儿视网膜病变（ROP）的发生率以及筛查方案对早产儿的有效性。基于这些目标，我们回顾了于尔居普·梅厄斯大学眼科1000例早产儿的病历。评估了ROP发生率、胎龄（GA）和出生体重（BW）的影响以及筛查方案的有效性。在本研究中，30.8%的婴儿观察到ROP，69.2%的婴儿未观察到。阈值ROP的检出率为7.0%。GA分别为≤26周、26 - 28周、29 - 30周和31 - 32周的婴儿中，阈值ROP的发生率分别为43.5%、20.0%、12.6%和8.8%。34周后出生的婴儿未观察到阈值ROP。11%的婴儿需要治疗。ROP治疗需求（11%）仅限于GA＜34周的婴儿。ROP发生率与GA和BW成反比。GA＞34周时无需治疗。为土耳其提出了一种新的ROP筛查方案，即：对GA＜34周且BW＜1800g的早产儿进行筛查。
