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Recognition and handling of discordant negative human epidermal growth factor receptor 2 classification by Oncotype DX in patients with breast cancer.

作者信息

Christgen Matthias, Harbeck Nadia, Gluz Oleg, Nitz Ulrike, Kreipe Hans H

出版信息

J Clin Oncol. 2012 Sep 10;30(26):3313-4; author reply 3314-5. doi: 10.1200/JCO.2012.42.1990. Epub 2012 May 29.

DOI:10.1200/JCO.2012.42.1990
PMID:22649153
Abstract
摘要

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The relationship between quantitative human epidermal growth factor receptor 2 gene expression by the 21-gene reverse transcriptase polymerase chain reaction assay and adjuvant trastuzumab benefit in Alliance N9831.
在联盟N9831研究中,通过21基因逆转录聚合酶链反应检测法测得的人表皮生长因子受体2基因定量表达与辅助性曲妥珠单抗疗效之间的关系。
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[Translational research and diagnostics for breast cancer].[乳腺癌的转化研究与诊断]
Pathologe. 2012 Nov;33 Suppl 2:282-90. doi: 10.1007/s00292-012-1645-1.