染色质缩减过程调控淡水桡足类 rRNA 基因拷贝数。
Chromatin Diminution Process Regulates rRNA Gene Copy Number in Freshwater Copepods.
机构信息
Vavilov Institute of General Genetics, Russian Academy of Sciences.
出版信息
Acta Naturae. 2010 Oct;2(4):52-7.
Abstract
The results of quantitative PCR (qPCR) presented in the paper clearly demonstrate that the sixteen-fold genome reduction inCyclops kolensisduring chromatin diminution (from 15.3 pg to 0.98 pg) results in a dramatic decrease in ribosomal RNA gene copy numbers in the genome of a somatic cell line by more than two orders of magnitude. The results presented allow for the consideration of the chromatin diminution as a mechanism of rDNA copy number regulation.
摘要
本文中的定量 PCR（qPCR）结果清楚地表明，在染色质缩减过程中（从 15.3pg 降至 0.98pg），Cyclops kolensis 的基因组减少了 16 倍，导致体细胞系基因组中的核糖体 RNA 基因拷贝数减少了两个以上数量级。本文所呈现的结果使得染色质缩减可以被视为 rDNA 拷贝数调控的一种机制。
Zotero 插件