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[棉布灸治疗带状疱疹:多中心随机对照试验]

[Treatment of herpes zoster with cotton sheet moxibustion: multicentral randomized controlled trial].

作者信息

Yang Jun-Xiong, Xiang Kai-Wei, Zhang Yu-Xue

机构信息

Department of Acupuncture and Moxibustion, Affiliated Hospital of Tongren Vocational Technical College, Tongren 554300, Guizhou Province, China.

出版信息

Zhongguo Zhen Jiu. 2012 May;32(5):417-21.

PMID:22650127
Abstract

OBJECTIVE

To compare the therapeutic effects and safety of herpes zoster treated by the cotton sheet moxibustion combined with the plum-blossom-needle tapping therapy to western medicine.

METHODS

The multicentral random controlled method was adopted, 120 cases of herpes zoster were randomly divided into a comprehensive treatment group and a western medication group, 60 cases in each one. In the comprehensive treatment group, the tapping therapy of plum blossom needle was applied to the foci, corresponding Jiaji (EX-B 2), Quchi (LI 11), Waiguan (TE 5), Zusanli (ST 36), Taichong (LR 3), etc. Afterward, the cotton sheet moxibustion was given. In western medication group, Acyclovir ointment for external application, Valaciclovir Hydrochloride tablets and Vitamin B1 for oral administration were prescribed. In 7 days of treatment, the clinical symptom score, effect time, efficacy and safety were observed before and after treatment between two groups. The recurrence of disease was followed up for 1 month.

RESULTS

In the comprehensive treatment group, the cured rate and the total effective rate were 80.0% (48/60) and 98.3% (59/60) separately, which were significantly better than 45.0% (27/60) and 71.7% (43/60) in western medication group separately (P < 0.01, P < 0.05). After treatment, in either group, the scores of clinical symptoms such as pain rating index (PRI), Visual Analogue Scale (VAS), present pain intensity (PPI), skin lesion and sleeping score, etc. were all reduced significantly (P < 0.01, P < 0.05). The score reducing was much more obvious in the comprehensive treatment group (P < 0.01, P < 0.05). In the comprehensive treatment group, the time of pain stopping, the time of blister stopping, the time of scarring and the time of healing were all shorter tha tn those in western medication group (P < 0.01, P < 0.05). In the follow-up observation, 1 case (1.6%) was recurred in the comprehensive treatment group and 8 cases (13.3%) were in western medication group. In western medication group, 6 cases presented mild adverse reactions.

CONCLUSION

The cotton sheet moxibustion combined with the plum-blossom-needle tapping therapy is advantageous at good efficacy, quick effect and short-time treatment for herpes zoster, which is apparently superior to the treatment with Acyclovir ointment for external application, Valaciclovir Hydrochloride tablets and Vitamin B1 for oral administration. It is the safe and effective therapy.

摘要

目的

比较棉片灸联合梅花针叩刺疗法与西药治疗带状疱疹的疗效及安全性。

方法

采用多中心随机对照法,将120例带状疱疹患者随机分为综合治疗组和西药治疗组,每组60例。综合治疗组采用梅花针叩刺病灶及相应夹脊(EX - B 2)、曲池(LI 11)、外关(TE 5)、足三里(ST 36)、太冲(LR 3)等穴位,之后给予棉片灸。西药治疗组外用阿昔洛韦软膏,口服盐酸伐昔洛韦片及维生素B1。治疗7天,观察两组治疗前后的临床症状评分、起效时间、疗效及安全性。随访1个月观察疾病复发情况。

结果

综合治疗组治愈率为80.0%(48/60),总有效率为98.3%(59/60),分别显著优于西药治疗组的45.0%(27/60)和71.7%(43/60)(P < 0.01,P < 0.05)。治疗后,两组疼痛分级指数(PRI)、视觉模拟评分法(VAS)、现时疼痛强度(PPI)、皮肤损害及睡眠评分等临床症状评分均显著降低(P < 0.01,P < 0.05)。综合治疗组评分降低更明显(P < 0.01,P < 0.05)。综合治疗组疼痛停止时间、水疱停止时间、结痂时间及愈合时间均短于西药治疗组(P < 0.01,P < 0.05)。随访观察中,综合治疗组有1例(1.6%)复发,西药治疗组有8例(13.3%)复发。西药治疗组有6例出现轻度不良反应。

结论

棉片灸联合梅花针叩刺疗法治疗带状疱疹疗效好、起效快、疗程短,明显优于外用阿昔洛韦软膏、口服盐酸伐昔洛韦片及维生素B1的治疗方法。是安全有效的治疗方法。

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