Ye Guoping, Su Meiling, Zhu Dingyu, Zhang Linyun, Lin Wang, Huang Li, Wu Mingxia
School of Acupuncture and Moxibustion, Fujian University of CM, Fuzhou 350122, China; Acupuncture and Moxibustion Department, the Second People's Hospital Affiliated to Fujian University of CM, Fuzhou 350003.
Community Health Service Center of Jiangtou Street, Huli District in Xiamen.
Zhongguo Zhen Jiu. 2017 Dec 12;37(12):1289-93. doi: 10.13703/j.0255-2930.2017.12.010.
To observe the effects of conventional western medication and joss stick moxibustion combined with pricking and cupping for herpes zoster in acute stage, and to explore its analgesic mechanism.
Seventy patients with acute herpes zoster were randomized into an observation group (33 cases after 2 dropping) and a control group (34 cases after 1 dropping). Patients in the observation group were treated with joss stick moxibustion combined with pricking and cupping at local points for 7 times, once every other day. Oral acyclovir, vitamin B and mecobalamin tablets were applied in the control group for continuous 14 days, and interferon injection was used for continuous 6 days, etc. The herpes evaluation indexes of blister stopping time, scab time and decrustation time as well as pain intensity were observed before and after treatment. Peripheral serum substance P (SP) content of herpes local situation was detected. The comprehensive effects were evaluated.
The blister stopping time, scab time and decrustation time in the observation group were shorter than those in the control group (all <0.05). There was no statistical significance for pain relief degree between the two groups (>0.05). The pain beginning to ease time and duration time in the observation group were better than those in the control group (both <0.05). The contents of SP in the two groups decreased after treatment (both <0.01), and it was better in the observation group (<0.05). The total effective rate of the observation group after treatment was 87.9% (29/33), and that of the control group was 85.3% (29/34), which were not statistically significant (>0.05). The cured rate of the observation group was better than that of the control group [66.7% (22/33) vs 58.8% (20/34), <0.05].
Joss stick moxibustion combined with pricking and cupping are effective for herpes zoster, which have quicker and good analgesic effects than conventional western medication. Its mechanism may be related to reducing the content of SP more fast and to a larger degree.
观察传统西药联合香艾条灸加刺络拔罐治疗急性期带状疱疹的疗效，并探讨其镇痛机制。
将70例急性期带状疱疹患者随机分为观察组（剔除2例后33例）和对照组（剔除1例后34例）。观察组采用香艾条灸加局部刺络拔罐治疗，每周3次，共7次。对照组口服阿昔洛韦、维生素B及甲钴胺片，连续14天，同时肌肉注射干扰素，连续6天等。观察治疗前后疱疹停止时间、结痂时间、脱痂时间等疱疹评价指标及疼痛程度。检测疱疹局部外周血清P物质（SP）含量，评价综合疗效。
观察组疱疹停止时间、结痂时间、脱痂时间均短于对照组（均P<0.05）。两组疼痛缓解程度比较差异无统计学意义（P>0.05）。观察组疼痛开始缓解时间及持续时间均优于对照组（均P<0.05）。两组治疗后SP含量均降低（均P<0.01），且观察组降低更明显（P<0.05）。观察组治疗后总有效率为87.9%（29/33），对照组为85.3%（29/34），差异无统计学意义（P>0.05）。观察组治愈率优于对照组[66.7%（22/33）比58.8%（20/34），P<0.05]。
香艾条灸加刺络拔罐治疗带状疱疹疗效确切，镇痛效果优于传统西药，其机制可能与更快、更大程度降低SP含量有关。
