一种成功的针对鞘内镇痛难治性癌症疼痛的姑息治疗干预方法。
A successful palliative care intervention for cancer pain refractory to intrathecal analgesia.
机构信息
Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
出版信息
J Pain Symptom Manage. 2012 Jul;44(1):124-30. doi: 10.1016/j.jpainsymman.2011.07.010. Epub 2012 May 30.
Abstract
Intrathecal delivery of opioid medications has been increasingly used to treat cancer pain that is refractory to conventional oral opioid therapy. We present a patient with complex and refractory cancer pain who failed both oral and intrathecal opioid therapy but responded to the interdisciplinary palliative care intervention in the acute palliative care unit. His morphine equivalent daily dose decreased by 94% over a 10-day period, and he had better pain control and improved function. This case highlights the importance of addressing and treating the psychosocial distress that contributes to the total pain expression.
摘要
鞘内给予阿片类药物已越来越多地用于治疗对常规口服阿片类药物治疗有反应的癌症疼痛。我们介绍了一位患有复杂和难治性癌症疼痛的患者，他既经口给予阿片类药物又经鞘内给予阿片类药物治疗均失败，但在急性姑息治疗病房接受姑息治疗多学科干预后得到了缓解。他的吗啡等效日剂量在 10 天内下降了 94%，疼痛得到了更好的控制，功能也得到了改善。这个病例强调了处理和治疗导致总疼痛表现的心理社会困扰的重要性。
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