Dept. of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.
Psychosomatics. 2013 Jan-Feb;54(1):94-7. doi: 10.1016/j.psym.2012.01.006. Epub 2012 May 30.
The subset of patients with late-life onset of bipolar disorder is widely recognized to represent an etiologically diverse group with high rates of neurologic comorbidities. Efforts to characterize the unique clinical and neurobiological features of this heterogeneous population have yielded inconsistent findings. Although there is growing evidence that geriatric-onset bipolar disorder is often attributable to a variety of secondary organic etiologies, we would like to present a case of bipolar disorder emerging in late life where no clear organic cause was identified. This case highlights the importance of a broad differential diagnosis when approaching new-onset manic symptoms among geriatric patients in an inpatient setting.
人们普遍认识到，老年期首发双相障碍患者亚组代表了一组具有高度神经共病率的病因学多样化群体。描述这种异质人群独特临床和神经生物学特征的努力得出了不一致的结果。尽管越来越多的证据表明老年期首发双相障碍通常归因于多种继发性有机病因，但我们想介绍一个在晚年出现的双相障碍病例，在该病例中未确定明确的器质性原因。该病例强调了在住院环境中，当老年患者出现新发躁狂症状时，进行广泛鉴别诊断的重要性。
