Dalai Pranav, Misra Madhukar
Contrib Nephrol. 2012;178:271-277. doi: 10.1159/000337890. Epub 2012 May 25.
An overwhelming majority of patients on dialysis reach end-stage renal disease (ESRD) secondary to diabetes mellitus (DM). Although renal transplantation offers the best option for these patients, shortage of available kidneys becomes a major impediment. Besides hemodialysis (HD), peritoneal dialysis (PD) is also a commonly offered dialysis modality to these patients. However, PD in diabetics poses unique challenges. A constant exposure to glucose in the dialysate may further worsen the internal milieu of hyperglycemic diabetic individuals. A number of factors may help improve outcomes in such patients. Protection of the peritoneal membrane and residual renal function (RRF) are extremely important in this regard. Close monitoring of blood glucose levels and prompt management of peritoneal and exit site infections can prevent long term complications. This brief review addresses some important measures that can help improve outcomes of such patients on PD.
绝大多数接受透析的患者因糖尿病(DM)继发终末期肾病(ESRD)。尽管肾移植为这些患者提供了最佳选择,但可用肾脏的短缺成为一个主要障碍。除了血液透析(HD)外,腹膜透析(PD)也是向这些患者常用的透析方式。然而,糖尿病患者的腹膜透析带来了独特的挑战。透析液中持续接触葡萄糖可能会进一步恶化高血糖糖尿病患者的内环境。一些因素可能有助于改善这类患者的预后。在这方面,保护腹膜和残余肾功能(RRF)极为重要。密切监测血糖水平以及及时处理腹膜和出口部位感染可预防长期并发症。本简要综述阐述了一些有助于改善接受腹膜透析的这类患者预后的重要措施。