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慢性腹膜透析在终末期肾衰竭糖尿病患者管理中的应用

Chronic peritoneal dialysis in the management of diabetics with terminal renal failure.

作者信息

Rubin J, Oreopoulos D G, Blair R D, Chisholm L D, Meema H E, deVeber G A

出版信息

Nephron. 1977;19(5):265-70. doi: 10.1159/000180899.

Abstract

Twelve diabetics with terminal renal failure were maintained on chronic peritoneal dialysis (PD) for 2-28 months (average 10 months). 7/12 survived more than 1 year. Blood glucose levels were well controlled by the use of supplemental, intradialysis, intraperitoneal insulin. The incidence of dialysis-related complications, including peritonitis was not significantly higher than in controls. Neurophysiological studies revealed a high incidence of neuropathy initially with progression in most patients. Radiological studies revealed initial vascular calcifications in 7 out of 12 patients with progression in 4. Retinopathy did not progress significantly. PD is a suitable alternative to hemodialysis in the management of end-stage diabetic nephropathy.

摘要

12名终末期肾衰竭糖尿病患者接受了2至28个月(平均10个月)的慢性腹膜透析(PD)治疗。12人中7人存活超过1年。通过补充透析内腹腔内胰岛素,血糖水平得到良好控制。包括腹膜炎在内的透析相关并发症的发生率并不显著高于对照组。神经生理学研究显示,大多数患者最初神经病变发生率较高且病情进展。放射学研究显示,12名患者中有7人最初出现血管钙化,4人病情进展。视网膜病变无明显进展。在终末期糖尿病肾病的治疗中,腹膜透析是血液透析的合适替代方法。

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