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双侧内镜下翼管神经切断术治疗中重度持续性变应性鼻炎的长期疗效

Long-term results of bilateral endoscopic vidian neurectomy in the management of moderate to severe persistent allergic rhinitis.

作者信息

Tan Guolin, Ma Yanhong, Li Heqing, Li Wei, Wang Jianjun

机构信息

Department of Otolaryngology-Head Neck Surgery, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

出版信息

Arch Otolaryngol Head Neck Surg. 2012 May;138(5):492-7. doi: 10.1001/archoto.2012.284.

Abstract

OBJECTIVE

To evaluate the long-term efficacy of bilateral endoscopic vidian neurectomy in the management of moderate to severe persistent allergic rhinitis.

DESIGN

A prospective reassessment of the postoperative long-term results of bilateral endoscopic vidian neurectomy using the Rhinoconjunctivitis Quality of Life Questionnaire and visual analog scale for patients with moderate to severe persistent allergic rhinitis.

SETTING

University hospital.

PATIENTS

A total of 236 patients with moderate to severe persistent allergic rhinitis were divided into the following 3 treatment groups: those who underwent bilateral endoscopic vidian neurectomy (group 1, n = 93), those who underwent partial inferior turbinectomy and/or septoplasty (group 2, n = 51), and those who received conservative therapy (controls, n = 92).

MAIN OUTCOME MEASURE

The patients' quality of life was assessed at 6 months, 1 year, and 3 years after undergoing the initial selected treatments for moderate to severe persistent allergic rhinitis. The complications were observed after treatment.

RESULTS

Data from 199 of 236 patients who had complete follow-up documents were statistically analyzed. The average posttreatment bilateral endoscopic vidian neurectomy scores of the Rhinoconjunctivitis Quality of Life Questionnaire and visual analog scale were significantly improved at 6 months, 1 year, and 3 years compared with pretreatment scores for group 1 (P < .00) and for those in groups 2 and 3 during the same period. By the patient's self-evaluation posttreatment, the percentages of much improved, improved, and not improved was 64.7% (55 cases), 24.7% (21 cases), and 10.6% (9 cases), respectively. The percentages were significantly higher for those in group 1 than for those in group 2 (P < .05). No severe complication occurred in all 3 patient groups.

CONCLUSION

In the hands of a well-trained surgeon bilateral endoscopic vidian neurectomy is an effective and safe technique in the management of moderate to severe persistent allergic rhinitis.

摘要

目的

评估双侧内镜下翼管神经切断术治疗中重度持续性变应性鼻炎的长期疗效。

设计

采用鼻结膜炎生活质量问卷和视觉模拟量表,对双侧内镜下翼管神经切断术治疗中重度持续性变应性鼻炎患者的术后长期效果进行前瞻性重新评估。

地点

大学医院。

患者

236例中重度持续性变应性鼻炎患者被分为以下3个治疗组:接受双侧内镜下翼管神经切断术的患者(第1组,n = 93)、接受部分下鼻甲切除术和/或鼻中隔成形术的患者(第2组,n = 51)以及接受保守治疗的患者(对照组,n = 92)。

主要观察指标

对中重度持续性变应性鼻炎患者进行初始选定治疗后6个月、1年和3年时评估患者的生活质量。治疗后观察并发症情况。

结果

对236例有完整随访资料的患者中的199例数据进行统计学分析。与第1组治疗前评分相比,第1组在治疗后6个月、1年和3年时鼻结膜炎生活质量问卷和视觉模拟量表的平均评分显著改善(P <.00),同期第2组和第3组患者的评分也有改善。根据患者治疗后的自我评估,改善明显、有所改善和未改善的百分比分别为64.7%(55例)、24.7%(21例)和10.6%(9例)。第1组患者的这些百分比显著高于第2组患者(P <.05)。所有3组患者均未发生严重并发症。

结论

在训练有素的外科医生手中,双侧内镜下翼管神经切断术是治疗中重度持续性变应性鼻炎的一种有效且安全的技术。

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