Hosoi Takayuki
Department of Clinical Research and Development, National Center for Geriatrics and Gerontology, Japan.
Clin Calcium. 2012 Jun;22(6):857-63.
FRAX® is a fracture risk assessment tool developed by WHO working groups. Ten-year risks for major osteoporotic fractures or hip fracture can be calculated with FRAX®. It has been discussed how to utilize FRAX® in the clinical settings in Japan. It was necessary to recognize the performance and limitation of this tool. In the Japanese guideline for prevention and treatment of osteoporosis 2011, a threshold of 10-year risk for major osteoporotic risk was proposed for the patients with osteopenia. It is emphasized that this is the proposal to use FRAX® in addition to the result of bone mineral density measurement and is not the proposal to use FRAX® as a screening tool. The way to utilize FRAX® as a screening tool should be investigated further.
FRAX®是由世界卫生组织工作小组开发的一种骨折风险评估工具。使用FRAX®可以计算出主要骨质疏松性骨折或髋部骨折的十年风险。在日本，人们已经讨论了如何在临床环境中使用FRAX®。有必要认识到该工具的性能和局限性。在《2011年日本骨质疏松症防治指南》中，针对骨质减少患者提出了主要骨质疏松性风险的十年风险阈值。需要强调的是，这是一项除骨密度测量结果外使用FRAX®的建议，而非将FRAX®用作筛查工具的建议。将FRAX®用作筛查工具的方法应进一步研究。
