Department of Dermatology, The George Washington University Medical Center, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA.
Dermatitis. 2012 Jan-Feb;23(1):22-6. doi: 10.1097/DER.0b013e31823d180f.
Allergic contact dermatitis is considered one of the most common causes of eyelid dermatitis. In addition to metals and topical antibiotics, fragrances have emerged as a leading source of contact allergy for individuals with this condition.
The objective of this study was to determine the added benefit of including a fragrance tray when patch testing patients presenting with eyelid dermatitis.
During a 4.5-year period, all patients with suspected allergic contact dermatitis involving the eyelids were patch tested with both standard and fragrance trays.
One hundred consecutive patients with eyelid dermatitis were patch tested. Of these patients, 42 (42%) tested positive for 1 or more allergens within the fragrance series. Of these patients, 15 (36%) had no fragrance markers detected on the standard series, and these allergens would therefore have been missed had fragrance series testing not been performed. Overall, fragrance markers within the standard series detected 73.2% (41/56) of cases of fragrance allergy.
Our results suggest that there may be a significant benefit to fragrance series testing in patients with eyelid dermatitis. Fragrance tray inclusion in this population may identify additional cases of fragrance allergy that are missed by the standard series.
过敏性接触性皮炎被认为是眼睑皮炎的最常见原因之一。除了金属和局部抗生素外，香料已成为此类患者接触过敏的主要来源。
本研究旨在确定在对患有眼睑皮炎的患者进行斑贴试验时包含香薰托盘是否会带来额外的益处。
在 4.5 年的时间里，所有疑似涉及眼睑的过敏性接触性皮炎的患者均进行了标准和香薰托盘斑贴试验。
100 例连续患有眼睑皮炎的患者接受了斑贴试验。在这些患者中，有 42 名（42%）对香薰系列中的 1 种或多种过敏原呈阳性反应。在这些患者中，有 15 名（36%）在标准系列中未检测到香薰标记物，如果不进行香薰系列检测，这些过敏原就会被遗漏。总的来说，标准系列中的香薰标记物检测出了 73.2%（41/56）的香薰过敏病例。
我们的研究结果表明，在眼睑皮炎患者中进行香薰系列检测可能会带来显著的益处。在该人群中包含香薰托盘可以发现标准系列遗漏的其他香薰过敏病例。
