香精系列在眼睑皮炎中的测试。

Fragrance series testing in eyelid dermatitis.

机构信息

Department of Dermatology, The George Washington University Medical Center, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA.

出版信息

Dermatitis. 2012 Jan-Feb;23(1):22-6. doi: 10.1097/DER.0b013e31823d180f.

DOI:10.1097/DER.0b013e31823d180f

PMID:22653065

Abstract

BACKGROUND

Allergic contact dermatitis is considered one of the most common causes of eyelid dermatitis. In addition to metals and topical antibiotics, fragrances have emerged as a leading source of contact allergy for individuals with this condition.

OBJECTIVES

The objective of this study was to determine the added benefit of including a fragrance tray when patch testing patients presenting with eyelid dermatitis.

METHODS

During a 4.5-year period, all patients with suspected allergic contact dermatitis involving the eyelids were patch tested with both standard and fragrance trays.

RESULTS

One hundred consecutive patients with eyelid dermatitis were patch tested. Of these patients, 42 (42%) tested positive for 1 or more allergens within the fragrance series. Of these patients, 15 (36%) had no fragrance markers detected on the standard series, and these allergens would therefore have been missed had fragrance series testing not been performed. Overall, fragrance markers within the standard series detected 73.2% (41/56) of cases of fragrance allergy.

CONCLUSIONS

Our results suggest that there may be a significant benefit to fragrance series testing in patients with eyelid dermatitis. Fragrance tray inclusion in this population may identify additional cases of fragrance allergy that are missed by the standard series.

摘要

背景

过敏性接触性皮炎被认为是眼睑皮炎的最常见原因之一。除了金属和局部抗生素外，香料已成为此类患者接触过敏的主要来源。

目的

本研究旨在确定在对患有眼睑皮炎的患者进行斑贴试验时包含香薰托盘是否会带来额外的益处。

方法

在 4.5 年的时间里，所有疑似涉及眼睑的过敏性接触性皮炎的患者均进行了标准和香薰托盘斑贴试验。

结果

100 例连续患有眼睑皮炎的患者接受了斑贴试验。在这些患者中，有 42 名（42%）对香薰系列中的 1 种或多种过敏原呈阳性反应。在这些患者中，有 15 名（36%）在标准系列中未检测到香薰标记物，如果不进行香薰系列检测，这些过敏原就会被遗漏。总的来说，标准系列中的香薰标记物检测出了 73.2%（41/56）的香薰过敏病例。