Nishinomiya Kyoritsu Neurosurgical Hospital, Imazuyamanakacho, Nishinomiya, Hyogo, Japan.
Neurosurgery. 2012 Sep;71(3):722-8; discussion 728. doi: 10.1227/NEU.0b013e318260fef7.
Management of overdrainage complications in shunted patients with idiopathic normal pressure hydrocephalus (INPH) remains a difficult task despite the use of programmable pressure valves.
To assess the usefulness of a quick reference table (QRT) algorithm for achieving a suitable initial programmable pressure valve setting in INPH patients who participated in the Study for INPH on Neurological Improvement (SINPHONI).
One hundred registered patients diagnosed with probable INPH were treated with ventriculoperitoneal shunts using Codman-Hakim programmable valves (CHPVs). In this series, the initial CHPV setting was decided prospectively according to the QRT algorithm. Shunt effectiveness, complications, and the number of CHPV readjustments during follow-up periods were investigated.
Eighty patients were considered better than shunt responders (more than 1 point improvement in modified Rankin scale at any follow-up period). Readjustments of CHPVs within 3 months after treatment with ventriculoperitoneal shunt were performed 56 times in 44 cases (44%, 0.56 times/patient). Low-pressure headache occurred in 9 patients, all of whom improved by readjustment alone. Nontraumatic subdural fluid collections and chronic subdural hematomas occurred in 15 cases (15%); however, most of the cases were subclinical and improved after CHPV readjustments alone. Burr hole irrigation was necessary in only 1 case.
Use of the QRT algorithm was associated with a decrease in postoperative CHPV readjustments and serious overdrainage complications during the follow-up period. The QRT algorithm is an easy, safe, and effective method for determining the initial CHPV pressure setting in INPH patients.
尽管使用了可编程压力阀,分流术治疗特发性正常压力脑积水(INPH)患者的过度引流并发症的管理仍然是一项艰巨的任务。
评估快速参考表(QRT)算法在参与 INPH 神经改善研究(SINPHONI)的 INPH 患者中实现合适初始可编程压力阀设置的有用性。
100 名确诊为可能 INPH 的患者接受了脑室-腹腔分流术,使用 Codman-Hakim 可编程阀(CHPV)。在该系列中,根据 QRT 算法前瞻性决定初始 CHPV 设置。研究了分流术的效果、并发症以及随访期间 CHPV 的调整次数。
80 名患者被认为是更好的分流术反应者(在任何随访期改良 Rankin 量表评分增加 1 分以上)。在脑室-腹腔分流术治疗后 3 个月内,44 例中有 44%(0.56 次/患者)进行了 56 次 CHPV 调整。9 例患者出现低压性头痛,均通过单独调整得到改善。15 例(15%)发生非创伤性硬脑膜下积液和慢性硬脑膜下血肿,但大多数病例为亚临床,单独调整 CHPV 后得到改善。仅 1 例需要颅骨钻孔灌洗。
使用 QRT 算法与术后 CHPV 调整次数减少和随访期间严重过度引流并发症相关。QRT 算法是确定 INPH 患者初始 CHPV 压力设置的一种简单、安全、有效的方法。