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乳胶过敏的诊断:Hev B 11 的重要性。

Diagnosis of latex allergy: the importance of hev B 11.

机构信息

Section of Allergology and Clinical Immunology, Department of Internal Medicine and Infectious Diseases, University of Bari Medical School, Bari, Italy.

出版信息

Int Arch Allergy Immunol. 2012;159(2):147-8. doi: 10.1159/000336654. Epub 2012 May 31.

DOI:10.1159/000336654
PMID:22653559
Abstract

We present the cases of 5 patients with a positive clinical history of cutaneous symptoms due to contact with latex products. A latex allergological assessment was made through skin prick tests (SPTs) both with commercial latex extracts and extemporaneous glove extracts, and serum-specific IgE to latex and glove-use tests. In addition, serum-specific IgE to recombinant allergens for Hevea brasiliensis was dosed. Molecular diagnostics in association with the glove-use test and, to a lesser extent, the SPTs with glove eluate are useful diagnostic tests to confirm the diagnosis of latex allergy in patients with mucocutaneous symptoms.

摘要

我们报告了 5 例因接触乳胶产品而出现皮肤症状的患者病例。通过皮肤点刺试验(SPTs),使用商业乳胶提取物和临时手套提取物,以及乳胶和手套使用试验的血清特异性 IgE,对乳胶过敏进行了评估。此外,还测定了对 Hevea brasiliensis 的重组过敏原的血清特异性 IgE。结合手套使用试验和(在较小程度上)手套洗脱液 SPTs 的分子诊断,对于确认有粘膜皮肤症状的乳胶过敏患者的诊断是有用的诊断测试。

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Diagnosis of latex allergy: the importance of hev B 11.乳胶过敏的诊断:Hev B 11 的重要性。
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Cloning and molecular characterization of the Hevea brasiliensis allergen Hev b 11, a class I chitinase.巴西橡胶树过敏原Hev b 11(一种I类几丁质酶)的克隆与分子特征分析
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Overview of component resolved diagnostics.成分分辨诊断概述。
Curr Allergy Asthma Rep. 2013 Feb;13(1):110-7. doi: 10.1007/s11882-012-0318-8.