Cancer Research UK Health Behaviour Research Centre, Department of Epidemiology and Public Health, UCL, London, UK.
J Med Screen. 2012 Jun;19(2):83-8. doi: 10.1258/jms.2012.012017. Epub 2012 May 31.
To assess the impact of media coverage of the UK Flexible Sigmoidoscopy Trial on colorectal screening uptake in England.
In April 2010, publication of the UK Flexible Sigmoidoscopy (FS) Trial results generated considerable media interest in both FS and colorectal cancer (CRC) generally.
We used routinely collected data from the south of England (excluding London) to analyse return of faecal occult blood test (FOBt) kits within 28 days of the invitation (early uptake) among 60-69 year olds, before (T1, n = 31,229), around the time of (T2, n = 39,571), and one month after (T3, n = 33,430) the FS publicity.
FOBt uptake over the whole period was 58.2%, with 38.4% of the kits returned within 28 days (early uptake). Across the three time periods, early uptake was 35.8% at T1, 39.4% at T2, and 39.7% at T3. Multivariate regression controlling for age, gender and socioeconomic status confirmed that uptake was higher if people received the FOBt kit around the time of the media coverage (T2: odds ratio [OR] = 1.17, 95% CI = 1.13-1.20), or one month after (T3: OR = 1.18, 95% CI = 1.15-1.22) than before (T1). Sub-group analyses demonstrated that the impact was stronger among previous non-responders than among first-time invitees or previous responders (P < 0.001).
Media coverage of the FS Trial appeared to have a small but positive impact on FOBt screening uptake, especially among people who had previously abstained from screening.
评估英国柔性乙状结肠镜检查试验的媒体报道对英格兰结直肠癌筛查参与率的影响。
2010 年 4 月，英国柔性乙状结肠镜（FS）试验结果公布后，FS 和结直肠癌（CRC）的媒体关注度都很高。
我们使用英格兰南部（不包括伦敦）的常规数据，分析了在 FS 宣传前后（T1，n=31229；T2，n=39571；T3，n=33430），60-69 岁人群在邀请后 28 天内返回粪便潜血试验（FOBt）试剂盒的情况（早期参与率）。
整个研究期间，FOBt 的参与率为 58.2%，其中 38.4%的试剂盒在 28 天内返回（早期参与率）。在三个时间点中，T1 时的早期参与率为 35.8%，T2 时为 39.4%，T3 时为 39.7%。多变量回归分析控制年龄、性别和社会经济地位后，证实如果人们在媒体报道期间（T2：比值比[OR] = 1.17，95%可信区间[CI] = 1.13-1.20）或一个月后（T3：OR = 1.18，95% CI = 1.15-1.22）收到 FOBt 试剂盒，其参与率会更高。亚组分析表明，这种影响在以前的非应答者中比首次被邀请者或以前的应答者更强（P<0.001）。
FS 试验的媒体报道似乎对 FOBt 筛查参与率产生了较小但积极的影响，尤其是在以前拒绝筛查的人群中。
