作为潜在抗炎剂的N-取代羰基氨基-1,2,3,6-四氢吡啶的合成
SYNTHESIS OF N-SUBSTITUTED CARBONYLAMINO-1,2,3,6-TETRAHYDROPYRIDINES AS POTENTIAL ANTI-INFLAMMATORY AGENTS.
作者信息
Ghaffari Mohammad A, Ardley Tiffany W, Gangapuram Madhavi, Redda Kinfe K
机构信息
College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, Florida, USA.
出版信息
Synth Commun. 2011;41(7):2615-2623. doi: 10.1080/00397911.2010.515335. Epub 2011 Jun 29.
Abstract
Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the corresponding N-substitutedimino-pyridinium ylides (4a-i and 8a, b) in absolute ethanol.
摘要
通过在无水乙醇中用硼氢化钠还原相应的N-取代亚氨基吡啶叶立德（4a-i和8a，b），合成了几种N-取代羰基/磺酰氨基-1,2,3,6-四氢吡啶（5a-i和9a，b）。
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