Bosco Chandra Kumar Asayas, Subramanyam S G, Kilpadi Arun B
St. John's national academy of health sciences, Sarjapur road, Bangalore, 605034 India.
Indian J Surg. 2011 Jun;73(3):178-83. doi: 10.1007/s12262-010-0116-2. Epub 2011 Feb 19.
Necrotising fasciitis is insidiously advancing soft tissue infection, characterized by widespread fascial necrosis. One of the most common conditions encountered in the clinical practice and which required clinical suspicion in patients who have less resistance to these infections. Especially in diabetic patients who are more prone for such infection due to low immunity and other reasons like early detection of these infections helps these patients to have a better recovery by aggressive surgical management and other measures required for the same. Literature has enough evidence on how serious this entity. Hence this study is designed in that aspect to help in early diagnosis and appropriate treatment. This study will help to determine the clinical presentation, the polymicrobial involved. The organisms most closely linked to necrotizing fasciitis are group A beta-hemolytic streptococci, although the disease may also be caused by other bacteria and their sensitivity patterns will help us to install appropriate antibiotics with the surgical management. And to compare our mortality rate with the other studies. A prospective descriptive study including all type II diabetic patients with necrotizing fasciitis over 3 years. Patients were evaluated in detail with respect to patient's history, examination, culture sensitivity and chart reviews and followed up using standard evaluation tools to measure the various outcomes. In 62 patients, the commonest clinical presentation was necrotic patch of skin and cellulites. The organisms cultured being beta hemolytic streptococci and E.Coli. The culture sensitivity pattern is to broad-spectrum antibiotics. The average stay in the hospital was about 13.74 days for the study group and the time delay in presentation is 6 days. Wagner's score is a useful tool for aiding the diagnosis. Patients without foot care had extensive lesions. And a mortality rate of 1.6 % in these patients. In an acutely swollen limb in a diabetic patient a high degree of suspicion of necrotizing fasciitis is required. A detailed foot care is warranted in these patients. An early extensive debridement is mandatory and key for a favorable outcome. And to start on broad- spectrum antibiotics is advisable. Wagner's scoring is helpful to predict the chances of a second surgery. With the above entities in mind the mortality rate of necrotizing fasciitis in type ii diabetes mellitus can be contained.
坏死性筋膜炎是一种隐匿进展的软组织感染,其特征为广泛的筋膜坏死。它是临床实践中最常见的病症之一,对于那些对这类感染抵抗力较低的患者需要临床怀疑。尤其是糖尿病患者,由于免疫力低下及其他原因,他们更容易发生此类感染。尽早发现这些感染有助于这些患者通过积极的手术治疗及其他相关措施实现更好的康复。文献中有足够的证据表明该病症的严重性。因此,本研究在这方面进行设计,以帮助早期诊断和恰当治疗。本研究将有助于确定临床表现、涉及的多种微生物。与坏死性筋膜炎联系最紧密的微生物是A组β溶血性链球菌,尽管该疾病也可能由其他细菌引起,它们的敏感性模式将帮助我们在手术治疗时选用合适的抗生素。并将我们的死亡率与其他研究进行比较。这是一项前瞻性描述性研究,纳入了3年期间所有患有坏死性筋膜炎的II型糖尿病患者。对患者进行了详细评估,包括患者病史、检查、培养敏感性及病历审查,并使用标准评估工具进行随访以衡量各种结果。在62例患者中,最常见的临床表现是皮肤坏死斑和蜂窝织炎。培养出的微生物为β溶血性链球菌和大肠杆菌。培养敏感性模式显示对广谱抗生素敏感。研究组的平均住院时间约为13.74天,就诊延迟时间为6天。瓦格纳评分是辅助诊断的有用工具。未进行足部护理的患者有广泛病变。这些患者的死亡率为1.6%。对于糖尿病患者急性肿胀的肢体,需要高度怀疑坏死性筋膜炎。这些患者需要进行详细的足部护理。早期广泛清创是取得良好预后必不可少的关键。建议开始使用广谱抗生素。瓦格纳评分有助于预测二次手术的可能性。考虑到上述因素,II型糖尿病患者坏死性筋膜炎的死亡率可以得到控制。