Morgan William R, Caldwell Michael D, Brady Jennifer M, Stemper Mary E, Reed Kurt D, Shukla Sanjay K
Department of Internal Medicine, Marshfield Clinic, Marshfield, Wisconsin, USA.
J Clin Microbiol. 2007 Feb;45(2):668-71. doi: 10.1128/JCM.01657-06. Epub 2006 Dec 13.
Benign papular eruption on the left leg of a 72-year-old diabetic man developed into rapidly spreading necrotizing fasciitis despite antimicrobial therapy and surgical debridements. This led to eventual amputation to control the infection. The etiological agent was a Staphylococcus aureus isolate harboring the enterotoxin gene cluster seg, sei, sem, sen, and seo but lacked all common toxin genes, including Panton-Valentine leukocidin.
一名72岁糖尿病男性左腿出现良性丘疹性皮疹,尽管接受了抗菌治疗和手术清创,仍发展为迅速蔓延的坏死性筋膜炎。这最终导致为控制感染而进行截肢。病原体是一株金黄色葡萄球菌分离株,携带肠毒素基因簇seg、sei、sem、sen和seo,但缺乏所有常见毒素基因,包括杀白细胞素。