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异位葡萄胎妊娠:一例报告

Ectopic molar pregnancy: a case report.

作者信息

Bousfiha Najoua, Erarhay Sanaa, Louba Adnane, Saadi Hanan, Bouchikhi Chahrazad, Banani Abdelaziz, El Fatemi Hind, Sekkal Med, Laamarti Afaf

机构信息

Department of gynecology obstetric I, Teaching Hospital, Hassan II, Fez, Morocco.

出版信息

Pan Afr Med J. 2012;11:63. Epub 2012 Apr 4.

Abstract

The incidence of hydatidiform moles is 1 per 1,000 pregnancies. Ectopic pregnancy occurs in 20 per 1,000 pregnancies. Thus, the incidence of the ectopic molar gestation is very rare. We report a case of tubal molar pregnancy diagnosed at the systematic histology exam of an ectopic pregnancy. We report the case of 32 years old nulliparus women who presented a vaginal bleeding, lower abdominal pain and 6 weeks amenorrhea corresponding to the last menstrual period. At the clinical examination, the arterial pressure was 100/60 mmHG. The gynecological examination was difficult because of lower abdominal pain. Serum gonadotropin activity was 3454 ui/l. Pelvic ultrasound revealed an irregular echogenic mass in the left adnexa. Diagnostic laparoscopy revealed a left-sided unruptured ampullary ectopic pregnancy. A left laparoscopic salpingectomy was performed. The systematic histologic test identified an ectopic partial molar pregnancy, which was confirmed by DNA ploidy image analysis. The patient was followed with weekly quantitative B-hCG titers until three successive B-hCG levels were negative. It is pertinent that clinicians take routine histological examination of tubal specimens in ectopic pregnancy very seriously in order to diagnose cases of ectopic molar gestations early and mount appropriate post treatment surveillance.

摘要

葡萄胎的发病率为每1000次妊娠中有1例。异位妊娠的发生率为每1000次妊娠中有20例。因此,异位葡萄胎妊娠的发生率非常罕见。我们报告一例在异位妊娠的系统组织学检查中诊断出的输卵管葡萄胎妊娠病例。我们报告的病例是一位32岁未生育的女性,出现阴道出血、下腹痛,自末次月经起停经6周。临床检查时,动脉血压为100/60 mmHg。由于下腹痛,妇科检查困难。血清促性腺激素活性为3454 ui/l。盆腔超声显示左侧附件区有一个不规则的回声团块。诊断性腹腔镜检查发现左侧壶腹部未破裂的异位妊娠。进行了左侧腹腔镜输卵管切除术。系统组织学检查确定为异位部分性葡萄胎妊娠,DNA倍体图像分析证实了这一诊断。对患者每周进行定量β - hCG检测,直至连续三次β - hCG水平呈阴性。临床医生应非常重视对异位妊娠输卵管标本进行常规组织学检查,以便早期诊断异位葡萄胎妊娠病例并进行适当的治疗后监测,这一点至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f59/3361201/d843f8d3676b/PAMJ-11-63-g003.jpg

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