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干细胞子宫内膜重建。

Endometrial reconstruction from stem cells.

机构信息

The Ritchie Centre, Monash Institute of Medical Research, Clayton, Victoria, Australia.

出版信息

Fertil Steril. 2012 Jul;98(1):11-20. doi: 10.1016/j.fertnstert.2012.05.004. Epub 2012 May 30.

DOI:10.1016/j.fertnstert.2012.05.004
PMID:22657248
Abstract

Adult stem cells have been identified in the highly regenerative human endometrium on the basis of their functional attributes. They can reconstruct endometrial tissue in vivo suggesting their possible use in treating disorders associated with inadequate endometrium. The identification of specific markers for endometrial mesenchymal stem cells and candidate markers for epithelial progenitor cells enables the potential use of endometrial stem/progenitor cells in reconstructing endometrial tissue in Asherman syndrome and intrauterine adhesions.

摘要

基于其功能特性,已在高度再生的人类子宫内膜中鉴定出成体干细胞。它们可以在体内重建子宫内膜组织,这表明它们可能用于治疗与子宫内膜不足相关的疾病。鉴定出子宫内膜间充质干细胞的特异性标志物和上皮祖细胞的候选标志物,使子宫内膜干细胞/祖细胞在重建 Asherman 综合征和宫腔粘连的子宫内膜组织中具有潜在的应用价值。

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Endometrial reconstruction from stem cells.干细胞子宫内膜重建。
Fertil Steril. 2012 Jul;98(1):11-20. doi: 10.1016/j.fertnstert.2012.05.004. Epub 2012 May 30.
2
Regenerating endometrium from stem/progenitor cells: is it abnormal in endometriosis, Asherman's syndrome and infertility?从干细胞/祖细胞再生子宫内膜:在子宫内膜异位症、Asherman 综合征和不孕中是否异常?
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Endometrial stem cells.子宫内膜干细胞
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Endometrial stem/progenitor cells and proliferative disorders of the endometrium.子宫内膜干细胞/祖细胞与子宫内膜增殖性疾病
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Adult stem cells in the endometrium.子宫内膜中的成人干细胞。
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Hormone and growth factor signaling in endometrial renewal: role of stem/progenitor cells.激素与生长因子信号在子宫内膜更新中的作用:干/祖细胞的角色
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Adult stem cells in endometrial regeneration: Molecular insights and clinical applications.子宫内膜再生中的成人干细胞:分子见解与临床应用。
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Endometrial stem/progenitor cells: the first 10 years.子宫内膜干细胞/祖细胞:首个十年
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Transplanted human embryonic stem cells as biological 'catalysts' for tissue repair and regeneration.移植的人类胚胎干细胞作为组织修复和再生的生物“催化剂”。
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Intrauterine infusion of autologous endometrial stem cells for the treatment of moderate and severe intrauterine adhesions: a before-and-after study.宫腔内输注自体子宫内膜干细胞治疗中重度宫腔粘连:一项前后对照研究。
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Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr 23. doi: 10.1007/s00210-025-04056-4.
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Novel therapeutic strategies for Asherman's syndrome: Endometrial regeneration using menstrual blood-derived stem cells.阿谢曼综合征的新型治疗策略:使用月经血源性干细胞进行子宫内膜再生。
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