John Farman Intensive Care Unit, Cambridge University Hospitals NHS Trust, Cambridge, UK.
J Hosp Infect. 2012 Jul;81(3):202-5. doi: 10.1016/j.jhin.2012.04.010. Epub 2012 Jun 1.
This study aimed to estimate the incidence of hospital transmission of influenza A subtype H1N1 [A(H1N1)], to identify high-risk areas for such transmission and to evaluate common characteristics of affected patients. In this single-centre retrospective cohort study, 10 patients met the criteria for hospital-acquired A(H1N1) infection over a three-month period. All affected patients required an escalation of their care and the mortality rate was 20%. Clinicians should be aware of the risk of nosocomial A(H1N1) infection that exists despite routine infection control measures and should consider additional control measures including vaccination of hospital inpatients and healthcare staff.
本研究旨在估计甲型 H1N1 流感（A(H1N1)）在医院内传播的发生率，确定此类传播的高风险区域，并评估受影响患者的常见特征。在这项单中心回顾性队列研究中，在三个月的时间内，有 10 名患者符合医院获得性 A(H1N1)感染的标准。所有受影响的患者都需要升级治疗，死亡率为 20%。尽管采取了常规感染控制措施，但临床医生仍应意识到存在医院获得性 A(H1N1)感染的风险，应考虑采取额外的控制措施，包括对住院患者和医护人员进行疫苗接种。
