人类X染色体的重组图谱。
A recombination map of the human X-chromosome.
作者信息
Del Mastro R G, Farndon P A, Kilpatrick M W
机构信息
Department of Clinical Genetics, Birmingham Maternity Hospital, University of Birmingham, UK.
出版信息
Hum Genet. 1990 Dec;86(2):228-30. doi: 10.1007/BF00197710.
A family with 11 normal boys has been typed with DNA probes spanning the whole of the X-chromosome to observe directly the recombination events in 11 meioses from one female. This has (a) identified apparent recombination hot-spots on the X-chromosome; (b) shown the positions and numbers of cross-overs that have occurred in the p and q arms; (c) not shown any cross-overs in the centromeric region and (d) enabled the calculation of the genetic length of the X-chromosome.
一个有11个正常男孩的家庭已使用跨越整个X染色体的DNA探针进行分型，以直接观察来自一名女性的11次减数分裂中的重组事件。这一过程（a）确定了X染色体上明显的重组热点；（b）显示了在p臂和q臂中发生交换的位置和数量；（c）未显示着丝粒区域有任何交换；（d）能够计算X染色体的遗传长度。
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