Müller E, Zabel P
Forschungsinstitut Borstel, Medizinische Klinik.
Immun Infekt. 1990 Oct;18(5):162-3.
Adequate IgG-replacement therapy as treatment of choice for patients with humoral immunodeficiencies has revolutionized the outcome of these disorders. The action of intravenous immunoglobulins (IVIG) in autoimmune diseases, especially in idiopathic thrombocytic purpura seems to be due to Fc-receptor blockade and immunomodifying qualities. Thus far, treatment for patients with subclass deficiencies is restricted to persons with recurrent infections.
充足的免疫球蛋白G替代疗法作为体液免疫缺陷患者的首选治疗方法,彻底改变了这些疾病的治疗结果。静脉注射免疫球蛋白(IVIG)在自身免疫性疾病,尤其是特发性血小板减少性紫癜中的作用似乎归因于Fc受体阻断和免疫调节特性。迄今为止,亚类缺陷患者的治疗仅限于反复感染的患者。