Dwyer J M
Adv Intern Med. 1987;32:111-35.
The availability of intravenous gamma globulin preparations that are safe and effective has revolutionized replacement therapy in those patients suffering primary or secondary hypogammaglobulinemia. The potential for controlling numerous autoimmune reactions with high-dose gamma globulin infusion is exciting and challenging. Unraveling the immunoregulatory mechanisms that interact with large doses of human IgG may teach us much about immunoregulation in general and the immunopathogenic mechanisms that lead to chronic disease for so many.
安全有效的静脉注射用丙种球蛋白制剂的出现，彻底改变了原发性或继发性低丙种球蛋白血症患者的替代疗法。大剂量输注丙种球蛋白来控制多种自身免疫反应的潜力令人兴奋且具有挑战性。弄清楚与大剂量人免疫球蛋白相互作用的免疫调节机制，可能会让我们对一般的免疫调节以及导致众多慢性疾病的免疫致病机制有更多了解。
