Pediatric Urology Unit, Ospedale Maggiore-Policlinico, Via della Commenda 10, 20122 Milan, Italy.
J Pediatr Urol. 2013 Jun;9(3):364-7. doi: 10.1016/j.jpurol.2012.05.005. Epub 2012 May 31.
Acquired megalourethra (AMU) after repair of proximal hypospadias can be a serious complication. An observational retrospective study of its incidence among different types of repair was performed.
Clinical charts of patients operated on for proximal hypospadias were reviewed.
all primary hypospadias operated in 1991-2004, with the meatus positioned in proximal penile, scrotal or perineal position.
Of 770 hypospadias cases treated, 130 (16%) were proximal. Seventy-two patients (55%) were treated using preputial flaps: 36 with a tubularized preputial island flap (TIF) and 36 an onlay island flap (OIF). Fifty-eight patients (45%) underwent staged repairs: Belt-Fuquà (BF) in 18 and Bracka procedure in 40 cases. After a mean follow up of 16 years (range 6-19) the overall incidence of complications for each technique was: TIF 36%; OIF 33%; BF 25%; two-stage Bracka 7.5%. The most common complication encountered was neo-urethral fistula. AMU occurred in only 5 cases, none with associated distal urethral stenosis, all in the TIF and OIF groups, and all successfully treated by reduction re-do urethroplasty.
A very small number of the patients operated using preputial island flaps techniques developed AMU. None of the staged repairs developed AMU, and this is the preferred choice in proximal hypospadias when the urethral plate requires division and/or substitution. All cases of AMU resolved after urethral tapering.
修复近端尿道下裂后获得性巨大尿道(AMU)可能是一种严重的并发症。对不同修复类型的发病率进行了观察性回顾性研究。
对接受近端尿道下裂手术的患者的临床病历进行了回顾。
1991 年至 2004 年间进行的所有原发性近端尿道下裂手术,尿道口位于阴茎近端、阴囊或会阴位置。
770 例尿道下裂病例中,近端尿道下裂 130 例(16%)。72 例患者(55%)采用包皮瓣治疗:36 例行管状包皮岛皮瓣(TIF),36 例行岛状皮瓣覆盖术(OIF)。58 例患者(45%)接受分期修复:Belt-Fuquà(BF)18 例,Bracka 术 40 例。平均随访 16 年(6-19 年)后,每种技术的并发症总发生率为:TIF 36%;OIF 33%;BF 25%;两阶段 Bracka 7.5%。最常见的并发症是新尿道瘘。仅 5 例出现 AMU,均无远端尿道狭窄,均发生在 TIF 和 OIF 组,均通过尿道再修复术成功治疗。
采用包皮岛皮瓣技术的患者中,极少数出现 AMU。分期修复均未出现 AMU,当尿道板需要分割和/或替代时,这是近端尿道下裂的首选方法。所有 AMU 病例经尿道缩窄后均得到解决。