Bernier-Chastagner V, Supiot S, Carrie C, Helfre S
Département de radiothérapie, centre Alexis-Vautrin, avenue de Bourgogne, Vandœuvre-lès-Nancy cedex, France.
Cancer Radiother. 2012 Jun;16 Suppl:S111-5. doi: 10.1016/j.canrad.2011.09.003. Epub 2012 Jun 1.
Stereotactic radiotherapy is a very high precision procedure, which has been limited to radiosurgery for a long time. Technological improvements allowed the development of radiotherapy in stereotactic conditions, leading to a lot of innovations. Previously indicated for cerebral pathologies, this procedure is now developed for extracerebral locations. In paediatrics, stereotactic radiotherapy is still limited, delivered precociously, due to the possibility of long-term late effects that needs to be addressed. This review reports the different useful conditions, technical evolutions, and the current validated paediatric indications, with differences from adults, and future directions.
立体定向放射治疗是一种精度非常高的治疗方法，长期以来一直局限于放射外科手术。技术的进步使得在立体定向条件下开展放射治疗成为可能，从而带来了诸多创新。该治疗方法以前主要用于脑部疾病，现在也用于脑外部位。在儿科领域，由于需要解决长期迟发效应的可能性，立体定向放射治疗仍然应用较少且开展较早。本综述报告了不同的适用情况、技术进展、目前已得到验证的儿科适应证、与成人的差异以及未来的发展方向。
