两种尿液细胞学检查预处理技术的比较
Comparison of two preparatory techniques for urine cytology.
作者信息
Dhundee J, Rigby H S
机构信息
Department of Cytology, Southmead Hospital, Bristol.
出版信息
J Clin Pathol. 1990 Dec;43(12):1034-5. doi: 10.1136/jcp.43.12.1034.
Two methods of preparation of urine for cytology were compared retrospectively. In method 1 cells in the urine were fixed after the preparation of the smear; in method 2 the cells were fixed before smear preparation. Urine cytology reports were correlated with subsequent histological analysis. The specificities of urine cytology using both methods were high (99%). The sensitivity using method 1 was 87%; using method 2 it was 65%. This difference was significant. The cell preparation technique therefore significantly changes the sensitivity of urine cytology. Cellular fixation after smear preparation is preferable to smear preparation after fixation.
对两种尿液细胞学检查的制备方法进行了回顾性比较。方法1是在涂片制备后对尿液中的细胞进行固定；方法2是在涂片制备前对细胞进行固定。尿液细胞学报告与随后的组织学分析相关联。两种方法的尿液细胞学特异性都很高（99%）。方法1的敏感性为87%；方法2的敏感性为65%。这种差异具有统计学意义。因此，细胞制备技术显著改变了尿液细胞学的敏感性。涂片制备后进行细胞固定优于固定后进行涂片制备。
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