Kuznetsov S L, Stepantsov V V
Kosm Biol Aviakosm Med. 1990 Sep-Oct;24(5):34-8.
Gastrocnemius muscle biopsies of 10 healthy volunteers, aged 27 to 44 years, who were exposed to head-down tilt (-8 degrees) for 370 days, were examined. The test subjects were subdivided into two equal groups that were assigned exercises of different type and workload. This prolonged bed rest caused atrophic changes in skeletal myofibers and decrease of their metabolic rate. Regular exercise produced a beneficial effect on the myofibers and reversed hypokinesia-induced changes but partially. The efficacy of the countermeasures depended, to a certain extent, on the time, when they were initiated, and the intensity, with which they were performed: the efficacy was higher and atrophic changes were delayed, if the subjects began exercising earlier and did it more actively.
对10名年龄在27至44岁之间、处于-8度头低位倾斜370天的健康志愿者的腓肠肌活检样本进行了检查。测试对象被分成两组，每组人数相等，两组进行不同类型和工作量的运动。这种长时间卧床休息导致骨骼肌纤维发生萎缩性变化并降低其代谢率。规律运动对肌纤维产生了有益影响，部分逆转了运动减少引起的变化。这些应对措施的效果在一定程度上取决于开始运动的时间以及运动的强度：如果受试者更早开始运动且运动更积极，效果会更好，萎缩性变化也会延迟。
