Guo G X, Xu C C, Hwang N H
Department of Biomedical Engineering, Memphis State University, Tennessee 38152.
J Biomed Eng. 1990 Nov;12(6):477-81. doi: 10.1016/0141-5425(90)90057-t.
The dynamics of leaflet motion in heart valve prostheses (HVP), and in particular the closing velocity, is believed to be related to the valve sound and possibly to the phenomenon of valve cavitation. This paper describes a non-intrusive laser sweeping technique enabling the study of leaflet motion. The principle of measurement and the equipment involved are presented, together with the results of two commercially available, 29 mm bileaflet mitral valves, a St. Jude Medical, and an Edwards Duromedic valve. Experiments were carried out in a pulsatile mock flow testing loop designed to mimic physiological pressure waveforms and ventricular contraction. Measurements of heart rate were made in the range 70-120 beats min-1, with a ventricular pressure slope range of 1800-5600 mm Hgs-1 and a cardiac output range of 5.0-7.5 litres min-1. Motion analysis of the measured data focuses on the velocity of the leaflet immediately before closure.
心脏瓣膜假体（HVP）中瓣叶运动的动力学，尤其是关闭速度，被认为与瓣膜声音以及可能与瓣膜空化现象有关。本文描述了一种非侵入式激光扫描技术，可用于研究瓣叶运动。介绍了测量原理和相关设备，以及两种市售的29毫米双叶二尖瓣（圣犹达医疗公司的和爱德华兹杜罗美迪克瓣膜）的测试结果。实验在一个脉动模拟血流测试回路中进行，该回路旨在模拟生理压力波形和心室收缩。心率测量范围为70 - 120次/分钟，心室压力斜率范围为1800 - 5600毫米汞柱/秒，心输出量范围为5.0 - 7.5升/分钟。对测量数据的运动分析重点关注瓣叶即将关闭前的速度。
