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[蜱传脑炎流行病学的新方面]

[New aspects of the epidemiology of tick-borne encephalitis].

作者信息

Alekseev A N

出版信息

Med Parazitol (Mosk). 1990 Sep-Oct(5):37-40.

PMID:2266902
Abstract

Profound studies of the mechanisms of virus transfer by bites and the behaviour of the infected ticks of male Ixodes ticks in the virus transfer and establish the effect of early and short-term suction of ticks in the onset of the disease. Preservation of saliva cement stopper in the skin of the infected vertebral host is of particular importance in the epidemiology and epizootiology of tick-borne encephalitis, as the cement cone in the skin may contain the quantity of the virus comparable with its concentration in the whole body of the tick. The experimental data suggest the predominant and more successful virus multiplication in the most viable and active ticks of the population as well as virus-induced stimulation of searching activity in the infected ticks. The attention is attracted to possible retention of the natural virus store by its elimination with the saliva of male ticks and virus exchange by sucking of the infected saliva from the affected focus on the skin by noninfected ticks fed together with infected insects, insensitive to tick-borne encephalitis virus.

摘要

深入研究蜱叮咬传播病毒的机制以及雄性硬蜱在病毒传播过程中受感染蜱的行为,并确定早期和短期蜱叮咬在疾病发病中的作用。在蜱传脑炎的流行病学和动物流行病学中,受感染脊椎动物宿主皮肤中唾液粘固塞的保存尤为重要,因为皮肤中的粘固锥可能含有与蜱全身病毒浓度相当的病毒量。实验数据表明,病毒在种群中最具活力和活性的蜱中大量繁殖且更为成功,同时病毒会刺激受感染蜱的搜索活动。值得关注的是,雄性蜱的唾液可能会清除天然病毒储存,而未感染蜱与感染昆虫一起进食时,通过吸食受感染皮肤病灶处的唾液,可能会发生病毒交换,这些未感染蜱对蜱传脑炎病毒不敏感。

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