School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, People's Republic of China.
Chem Commun (Camb). 2012 Jul 11;48(54):6857-9. doi: 10.1039/c2cc31529g. Epub 2012 Jun 6.
New amphiphilic ABC triblock copolymers have been designed and self-assembled into water-dispersible and biodegradable polymer micelles, which exhibit good antibacterial activities without quaternary ammonium moieties or the loading of any external antibiotics due to the increased local concentration of cationic charge in the polymer micelles compared to the un-self-assembled individual polymer chains.
新的两亲性 ABC 三嵌段共聚物被设计并自组装成水分散和可生物降解的聚合物胶束，由于与未自组装的单个聚合物链相比，聚合物胶束中阳离子电荷的局部浓度增加，因此表现出良好的抗菌活性，而无需季铵基团或负载任何外部抗生素。
