Critical Care and Neuroscience, Murdoch Children's Research Institute, Australia.
J Pediatr Psychol. 2012 Aug;37(7):745-54. doi: 10.1093/jpepsy/jss070. Epub 2012 Jun 4.
Typically, studies on outcomes after traumatic brain injury (TBI) have investigated whether a younger age at injury is associated with poorer recovery by comparing 2 age groups rather than participants injured across childhood. This study extended previous research by examining whether the influence of age on recovery fits an early vulnerability or critical developmental periods model.
Children with a TBI (n = 181) were categorized into 4 age-at-injury groups-infant, preschool, middle childhood, and late childhood--and were evaluated at least 2-years post-TBI on IQ.
Overall, the middle childhood group had lower IQ scores across all domains. Infant and preschool groups performed below the late childhood group on nonverbal and processing speed domains.
Contrary to expectations, children injured in middle childhood demonstrated the poorest outcomes; this age potentially coincides with a critical period of brain and cognitive development.
通常，关于创伤性脑损伤（TBI）后结果的研究通过比较 2 个年龄组而非整个儿童时期受伤的参与者，来研究受伤时年龄较小是否与恢复较差相关。本研究通过检查年龄对恢复的影响是否符合早期脆弱性或关键发育阶段模型，扩展了以往的研究。
将患有 TBI 的儿童（n=181）分为 4 个受伤时年龄组-婴儿期、学龄前、学龄中期和学龄晚期，并在 TBI 后至少 2 年进行智商评估。
总体而言，所有领域的学龄中期儿童的智商得分较低。婴儿期和学龄前组在非言语和加工速度领域的表现低于学龄晚期组。
与预期相反，学龄中期受伤的儿童表现出最差的结果；这个年龄段可能与大脑和认知发展的关键时期相吻合。
