Greene Rachel K, Rich-Wimmer Natalia, Williams Cydni N, Hall Trevor A
Department of Pediatrics, Division of Pediatric Psychology, Oregon Health and Science University, Portland, OR 97239, USA.
Department of Pediatrics, Division of Critical Care, Oregon Health and Science University, Portland, OR 97239, USA.
Children (Basel). 2022 Oct 28;9(11):1648. doi: 10.3390/children9111648.
Children and adolescents who survive the pediatric intensive care unit (PICU) with an acquired brain injury (ABI) often demonstrate a variety of physical, cognitive, emotional/behavioral, and social sequelae termed post-intensive care syndrome (PICS). Social communication and interaction challenges have also been observed clinically, and there is growing literature documenting these occurrences in youth following ABI. The extent of these social changes varies among patients, and a subset of patients go on to exhibit social and behavioral profiles closely resembling those of autistic youth. We reviewed empirical research regarding social functioning in youth following ABI, as well as the overlap between individuals with ABI and autistic youth, published from January 2009 to August 2022 on PubMed and Scopus databases. Clinical case examples from a well-established post-PICU follow-up program are also provided to exemplify the complexity of this phenomenon.
在儿科重症监护病房（PICU）中幸存下来且患有获得性脑损伤（ABI）的儿童和青少年，常常会出现一系列身体、认知、情感/行为以及社会方面的后遗症，即所谓的重症监护后综合征（PICS）。临床上也观察到了社交沟通和互动方面的挑战，并且有越来越多的文献记录了ABI后青少年中出现的这些情况。这些社会变化的程度在患者之间各不相同，并且有一部分患者会表现出与自闭症青少年极为相似的社会和行为特征。我们回顾了2009年1月至2022年8月在PubMed和Scopus数据库上发表的关于ABI后青少年社会功能以及ABI患者与自闭症青少年之间重叠情况的实证研究。还提供了一个成熟的PICU后随访项目中的临床案例，以例证这一现象的复杂性。
