继发于成人斯蒂尔病的噬血细胞综合征，但与淋巴瘤非常相似。
Hemophagocytic syndrome secondary to adult-onset Still's disease but very similar to lymphoma.
作者信息
Zhang Xin-Hua, Han Yong-Mei, Wang Wen-Wen, Cheng Hao, Zhu Ke-Jian
机构信息
Department of Dermatology and Rh.eumatology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
出版信息
Int J Clin Exp Pathol. 2012;5(4):377-81. Epub 2012 Apr 16.
Abstract
Hemophagocytic syndrome (HPS) is a clinicopathologic entity characterized by increased proliferation and activation of benign macrophages with hemophagocytosis throughout the reticuloendothelial system. HPS may be primary, or secondary to malignancy, infections, auto-immune diseases and pharmacotherapy. In patients with adult-onset Still's disease (AOSD), HPS is a rare but life-threatening complication. Herein, we described a female patient with HPS secondary to AOSD. During the therapy, giant gastric ulcer similar to lymphoma developed after treatment with corticosteroid and nonsteroidal anti-inflammatory drugs.
摘要
噬血细胞综合征（HPS）是一种临床病理实体，其特征是良性巨噬细胞在整个网状内皮系统中增殖和激活增加，并伴有噬血细胞现象。HPS 可能是原发性的，或继发于恶性肿瘤、感染、自身免疫性疾病和药物治疗。在成人斯蒂尔病（AOSD）患者中，HPS 是一种罕见但危及生命的并发症。在此，我们描述了一名继发于 AOSD 的 HPS 女性患者。在治疗期间，使用皮质类固醇和非甾体抗炎药治疗后出现了类似于淋巴瘤的巨大胃溃疡。
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