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伴发斯蒂尔病的噬血细胞性淋巴组织细胞增生症:一例报告

Hemophagocytic lymphohistiocytosis accompanying Still's disease: A case report.

作者信息

Ahmadzadeh Arman, Babadi Neda, Farsad Faraneh, Babadi Saba, Assar Shirin

机构信息

Rheumatology Ward of Loghman Hakim Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.

Department of Adult Rheumatology, Loghman Hakim Hospital, School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2023 Oct 10;11(10):e7955. doi: 10.1002/ccr3.7955. eCollection 2023 Oct.

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic disease that occurs due to immune system dysfunction. Clinical manifestations of this disease are fever, increased ferritin level, cytopenia, and hemophagocytosis in the biopsy report of the bone marrow. We report a 36-year-old woman referred to our hospital with persistent fever, arthralgia in interphalangeal joints, and cutaneous rash on the trunk, was subsequently diagnosed as an adult-onset Still's disease (AOSD), and after bone marrow aspiration, HLH was diagnosed with her.

摘要

噬血细胞性淋巴组织细胞增生症(HLH)是一种由于免疫系统功能障碍而发生的罕见血液疾病。该疾病的临床表现为发热、铁蛋白水平升高、血细胞减少以及骨髓活检报告中的噬血细胞现象。我们报告一例36岁女性,因持续发热、指间关节疼痛及躯干皮疹转诊至我院,随后被诊断为成人斯蒂尔病(AOSD),骨髓穿刺后又被诊断为HLH。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d54/10565094/61bc566490a8/CCR3-11-e7955-g001.jpg

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