Raspollini Maria Rosaria, Masieri Lorenzo, Tosi Nicola, Santucci Marco
Division of Histology and Molecular Diagnostics, University Hospital Careggi, University of Florence, Florence, Italy.
Arch Ital Urol Androl. 2011 Dec;83(4):210-2.
Blue nevus is a stromal melanin deposition, which is microscopically characterized by deeply pigmented melanin-filled spindle cells within the fibromuscular stroma. Cases with prominent melanosis such as those with grossly visible pigment are uncommon. Melanocytic lesions of the prostate are incidental findings with no evidence of malignant transformation. There have only been very few reports of a malignant melanoma of primary prostatic origin. We report an incidental finding of a blue nevus of the prostate, in a radical prostatectomy specimen, in a 64-years-old man with a pre-operative ecographic image of peripheral hypoechogenic nodule. The are very few reports of blue nevi associated to prostatic adenocarcinoma, but none has been evidentiated before surgery as a distinct ultrasound lesion interpreted as adenocarcinoma, therefore inducing the clinician to perform biopsies and consequently a radical prostatectomy.
蓝色痣是一种间质黑色素沉积,其显微镜下特征为纤维肌肉间质内充满黑色素的深色素沉着梭形细胞。黑色素沉着明显的病例,如肉眼可见色素沉着的病例并不常见。前列腺的黑素细胞病变是偶然发现,无恶性转化证据。原发性前列腺起源的恶性黑色素瘤仅有极少数报道。我们报告了一例在前列腺根治性切除标本中偶然发现的前列腺蓝色痣,患者为一名64岁男性,术前超声图像显示外周低回声结节。关于与前列腺腺癌相关的蓝色痣报道极少,但术前均未作为一种被解释为腺癌的独特超声病变而被发现,因此导致临床医生进行活检并进而实施前列腺根治性切除术。