机构养老老年人停用维持剂量地高辛的情况
Withdrawal of maintenance digoxin from institutionalized elderly.
作者信息
Macarthur C
机构信息
Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada.
出版信息
Postgrad Med J. 1990 Nov;66(781):940-2. doi: 10.1136/pgmj.66.781.940.
Chronic use of digitalis is common amongst the institutionalized elderly. Associated with digitalis use is the potential for toxicity and/or adverse reactions. In this study maintenance digoxin was withdrawn from 14 elderly nursing home residents in sinus rhythm. Subjects were followed over 18 months for evidence of dysrhythmia or heart failure. One resident had an episode of supraventricular tachycardia which required digoxin to be restarted. One resident developed left heart failure, treated with oral diuretic. For 12 of the 14 residents, withdrawal of maintenance digoxin was achieved without deleterious effect. This study suggests that maintenance digoxin may be withdrawn safely in elderly nursing home residents in sinus rhythm and without history of atrial dysrhythmia.
洋地黄的长期使用在机构养老的老年人中很常见。使用洋地黄存在中毒和/或不良反应的可能性。在本研究中，14名窦性心律的老年疗养院居民停用了维持剂量的地高辛。对受试者进行了18个月的随访，以观察心律失常或心力衰竭的迹象。一名居民发生了室上性心动过速，需要重新开始使用地高辛。一名居民出现左心衰竭，接受了口服利尿剂治疗。在14名居民中的12名中，停用维持剂量的地高辛没有产生有害影响。这项研究表明，窦性心律且无房性心律失常病史的老年疗养院居民可以安全停用维持剂量的地高辛。
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