Taguchi Animal Hospital, Kamisatochou, Kodamagun, Japan.
Microbiol Immunol. 2012 Aug;56(8):579-82. doi: 10.1111/j.1348-0421.2012.00475.x.
Domesticated adult dogs with antibody titer classified as below 'high' to one or more of canine distemper virus (CDV), canine parvovirus type-2 (CPV-2) and canine adenovirus type-1 (CAdV-1) were then given an additional inoculation, and the effectiveness of this booster evaluated 2 months later. Consequently, CDV and CAdV-1 antibody titer experienced a significant increase, but the same effect was not observed in the antibody titer of CPV-2. These findings suggest that with additional inoculation, a booster effect may be expected in increasing antibody titers for CDV and CAdV-1, but it is unlikely to give an increase in CPV-2 antibody titer.
随后，对抗体滴度分类为“低”或“高”以下的犬瘟热病毒（CDV）、犬细小病毒 2 型（CPV-2）和犬腺病毒 1 型（CAdV-1）的驯化成年犬进行了额外接种，并在 2 个月后评估了这种加强针的效果。结果，CDV 和 CAdV-1 的抗体滴度显著增加，但 CPV-2 的抗体滴度没有观察到相同的效果。这些发现表明，通过额外接种，可以预期加强针会增加 CDV 和 CAdV-1 的抗体滴度，但不太可能增加 CPV-2 的抗体滴度。
