Lechner Elizabeth S, Crawford P Cynda, Levy Julie K, Edinboro Charlotte H, Dubovi Edward J, Caligiuri Randy
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA.
J Am Vet Med Assoc. 2010 Jun 15;236(12):1317-21. doi: 10.2460/javma.236.12.1317.
To determine the proportion of dogs entering an animal shelter with protective antibody titers (PATs) for canine distemper virus (CDV) and canine parvovirus (CPV) and identify factors associated with having a PAT.
Cross-sectional study.
431 dogs admitted to an open-admission municipal animal shelter in north central Florida with a history of infectious disease outbreaks.
Blood was collected from dogs on the day of admission to the shelter. Antibody titers for CDV and CPV were measured by virus neutralization and hemagglutination inhibition, respectively. Age, sex, neuter status, address of origin, source (stray or previously owned), health status (healthy or not healthy), and outcome (adoption, euthanasia, or reclaimed by owner) data were also collected.
Overall, 64.5% (278/431) of dogs had insufficient titers for antibodies against CDV, CPV, or both. A total of 153 (35.5%) dogs had PATs for both CDV and CPV, 33 (7.7%) had PATs for CDV but not CPV, 136 (31.5%) had PATs for CPV but not CDV, and 109 (25.3%) did not have PATs for either virus. Older dogs were more likely to have PATs for CDV and CPV. Neutered dogs were more likely to have PATs for CDV. Factors not associated with having a PAT included source, health status, and type of community from which the dog originated.
Most dogs had insufficient antibody titers for CDV, CPV, or both at the time of admission to the animal shelter. Findings support current guidelines recommending vaccination of all dogs immediately upon admission to shelters, regardless of source or physical condition.
确定进入动物收容所的犬只中，对犬瘟热病毒（CDV）和犬细小病毒（CPV）具有保护性抗体滴度（PATs）的比例，并识别与拥有PAT相关的因素。
横断面研究。
431只进入佛罗里达州中北部一家开放式市政动物收容所的犬只，这些犬只都有传染病爆发史。
在犬只进入收容所当天采集血液。分别通过病毒中和试验和血凝抑制试验测量CDV和CPV的抗体滴度。还收集了年龄、性别、绝育状态、来源地址、来源（流浪犬或曾被饲养犬）、健康状况（健康或不健康）以及结局（被领养、安乐死或被主人领回）等数据。
总体而言，64.5%（278/431）的犬只针对CDV、CPV或两者的抗体滴度不足。共有153只（35.5%）犬只对CDV和CPV均具有PATs，33只（7.7%）对CDV具有PATs但对CPV不具有，136只（31.5%）对CPV具有PATs但对CDV不具有，109只（25.3%）对两种病毒均不具有PATs。年龄较大的犬只更有可能对CDV和CPV具有PATs。已绝育的犬只更有可能对CDV具有PATs。与拥有PAT无关的因素包括来源、健康状况以及犬只所来自的社区类型。
大多数犬只在进入动物收容所时针对CDV、CPV或两者的抗体滴度不足。研究结果支持当前指南，即建议所有犬只进入收容所后立即进行疫苗接种，无论其来源或身体状况如何。
