Rendon Center for Dermatology and Aesthetic Medicine/Skin Care Research, Inc., Boca Raton, FL 33486, USA.
J Cosmet Dermatol. 2012 Jun;11(2):93-100. doi: 10.1111/j.1473-2165.2012.00609.x.
Facial rejuvenation techniques have evolved in recent decades driven by a paradigm shift to restoration of lost volume, and an increase in the number of available products. As clinical experience has increased, practitioners have further refined the use of these products.
To share observations and practical recommendations based on clinical experience with the aesthetic use of injectable poly-l-lactic acid (PLLA) in patients followed for up to 5 years.
Literature review and retrospective case history review of the first 100 patients treated with injectable PLLA, many of whom have been followed for over 5 years.
Use of injectable PLLA, alone or in combination with other products, has provided excellent and long-lasting (up to 5 years) aesthetic results for most of the reviewed patients. Typically, patients have received one or two touch-up sessions between years 2 and 4 after initial full correction. There were minimal adverse events of papule formation; these eventually resolved.
Injectable PLLA is a safe and effective option for achieving long-term patient satisfaction with soft-tissue augmentation.
近年来，随着恢复失去的体积的范式转变和可用产品数量的增加，面部年轻化技术得到了发展。随着临床经验的增加，从业者进一步完善了这些产品的使用。
分享在长达 5 年的随访中，基于对聚左旋乳酸（PLLA）在美容应用方面的临床经验观察和实用建议。
对 100 名接受注射 PLLA 治疗的患者进行文献复习和回顾性病历复习，其中许多患者随访时间超过 5 年。
在大多数接受回顾的患者中，单独使用或与其他产品联合使用注射 PLLA 已为他们提供了极好且持久（长达 5 年）的美学效果。通常，患者在初次完全矫正后 2 至 4 年内接受一次或两次补打治疗。丘疹形成的不良反应很少见，最终会自行消退。
注射 PLLA 是一种安全有效的选择，可以实现长期的患者对软组织填充的满意度。
